It is recognized that exposure to tremendously loud sounds—whether it is a firecracker, an explosion, or even a show—can result in everlasting loss of hearing. However, recognizing how to treat noise-stimulated hearing loss has majorly remained an obscurity, but this might ultimately revolutionize, thanks to a new study by the researchers from the Keck School of Medicine of USC.
To develop a cure for noise-stimulated hearing loss, the team initially had to comprehend its mechanisms. They developed a device making use of innovative tiny optics to picture within the cochlea, the inner ear’s hearing piece, and the mice were exposed to a loud noise resembling that of a roadside explode.
They established that 2 things occur after contact with a loud noise: the inner ear loads with surplus fluid, resulting in the neurons’ death and sensory hair cells—the cells that sense sound and translate it to neural signals—die. The sensory hair cells, as well as neurons, have crucial roles to play in hearing.
The team discovered that the death sensory hair cell took place instantly following contact with loud noise and was irrevocable. Neuron damage, nevertheless, had a deferred commencement, opening a path to prospect for treatment.
The fluid buildup within the inner ear took place over the duration of few hours subsequent to loud noise exposure and held high potassium concentrations. To overturn the consequences of the potassium and decrease the buildup of fluid, sugar- and salt-based solutions were administered into the middle ear, simply through the eardrum, 3 Hours following the noise exposure. The team established that treating with these solutions averted 45–64% of neuron loss, proposing that the treatment might present a means to protect hearing function.
Recently, DocPanel declared an affiliation with the USC Keck School of Medicine Department of Radiology that will provide the access to the consumers to the 60 world-class radiology sub-specialists of Keck.
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